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In this article, we will briefly discuss different methods to detect and segment nuclei and in particular, give examples of how artificial intelligence (AI) Deep Learning (DL) methods are increasingly being applied within our organisation to streamline our image...
Following on from our previous article on Tertiary Lymphoid Structures (TLS), in which OracleBio clinical pathologist Gabriele Kohnen discussed the potential role of Tertiary Lymphoid Structures in normal and diseased tissues, this article describes some recent work...
A neoplasm is a population of abnormal cells which persist and proliferate excessively. Almost all cell types and tissues give rise to neoplasia: epithelium, connective tissue, bone marrow, lymphoid, neural tissue &c, but nine out of 10 cancers are invasive...
Multiplex IF assays are highly valuable in generating data that enables a deeper understanding of cell phenotypes, their functional status, and spatial relationships within tissues across different diseases or therapeutic interventions. However, the staining of...
Bowel cancer is currently the second most deadly cancer in the UK, accounting for 10% of all cancer deaths. The current screening protocol for this type of malignancy involves a colonoscopy for patients who test positive for blood in their stool. About one in three of...
Imagine an image 20,000 times the file size of a standard iPhone photo... and imagine hundreds of these images having to be transferred, stored, and analysed to reveal their secrets. That's the reality and the challenge facing researchers working in the field of...
Microscope slide scanning to produce digital histology images is a recent technology which is of interest to both histologists and pathologists. Microscope slide scanning to produce digital images is routinely used in various teaching organisations, however its...
Selecting the right therapeutic disease indication in which to trial new therapies is a notoriously difficult task. Failure to choose the right indication can result in failure in Phase II/III trials resulting in drug discovery programs being halted which, given...