In this article, OracleBio’s Senior Pathologist, Dr. Gabriele Kohnen, gives her perspective on the proposed role of tertiary lymphoid structures within the immune system and how better understanding their prevalence, cellular content and distribution may provide...
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Where does Cancer come from? – Cancer precursors and their terminology
A neoplasm is a population of abnormal cells which persist and proliferate excessively. Almost all cell types and tissues give rise to neoplasia: epithelium, connective tissue, bone marrow, lymphoid, neural tissue &c, but nine out of 10 cancers are invasive...
Still at the Cutting Edge: Microtomy and Digital Pathology
In 2012, my friend and colleague Dr. Gabriele Kohnen salvaged three identical old microtomes from a skip (dumpster for our friends in the US!). After storing them in her garage for a decade, she gave them to me. I guessed they might date from the 1930s, but...
The Silence of the Pathologists: Fixation in Histology and Histopathology
‘Welcome to Fight Club. The first rule of Fight Club is: you do not talk about Fight Club.’ (Chuck Palauniak 1996). Fight Club and Histopathology may not overlap widely, but their intersection is not empty. Dr Wilfred Weinstein of Los Angeles spoke of ‘The Silence...