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In this article, OracleBio’s Senior Pathologist, Dr. Gabriele Kohnen, gives her perspective on the proposed role of tertiary lymphoid structures within the immune system and how better understanding their prevalence, cellular content and distribution may provide...
A neoplasm is a population of abnormal cells which persist and proliferate excessively. Almost all cell types and tissues give rise to neoplasia: epithelium, connective tissue, bone marrow, lymphoid, neural tissue &c, but nine out of 10 cancers are invasive...
Quantifying the number, type and distribution of immune cells in oncology tissue is key to obtaining a greater understanding of the actions of immunotherapies as part of immuno-oncology research. With the advent of advanced quantitative digital histopathology...
According to the American Cancer Society, an estimated 88,000 new cases of gynecologic cancer are diagnosed per year in the U.S., and over 29,000 American women will lose their battle with this deadly disease. Over the past 12 months, OracleBio has supported work lead...
The characterisation of immune cells within the tumor microenvironment and their potential impact on cancer treatment and prognosis has been the subject of intense investigation over recent years. Non-small cell lung cancer (NSCLC) patients have impaired immune...
The development of new oncology therapies is routinely supported through the use of various xenograft models. Identifying the most suitable models for use in pre-clinical oncology programmes is key to establishing a successful translational R&D strategy. The...