⚡ Article Synopsis: In this article, OracleBio's Marketing Manager, Mark Laurie, wraps up some of this year’s highlights and gives you a peek at what’s to come in 2023!As 2022 draws to a close, it’s a good time to reflect on the year and appreciate how much we’ve...
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6 Ways to Improve the Quality of Quantitative Histopathology Data in 2022
⚡ Article Synopsis: In this article, OracleBio's Deputy Clinical Operations Manager, Nicole Couper, outlines 6 of the most prevalent issues encountered in Histopathology that hinder or negatively impact data quality.The generation of high-quality and robust...
Improving multiplex IF image analysis workflows: Does the perfect solution to autofluorescence exist?
⚡ Article Synopsis: In this article, OracleBio Image Analysis Scientist - Cristina Suanno, discusses ways to overcome autofluorescence, a common issue associated with multiplex immunofluorescent stained images.There are measures that can be taken at the tissue...
Utilizing AI to improve analysis accuracy and turnaround time for Preclinical tumor model IHC studies
⚡ Article Synopsis: In this article, we highlight a previous webinar case study where we utilized AI deep learning techniques to improve the accuracy and turn-around time for quantification of cytotoxic T-cell (CD8 marker), macrophage (F4/80 marker), and vasculature...
The use and value of the preclinical Bleomycin model in Drug Development for Idiopathic Pulmonary Fibrosis (IPF)
⚡ Article Synopsis: In this article, OracleBio has come together with one of our partners, TherapeutAix, who provide strategic and operational support for drug development projects, to provide our collective thoughts on the use and value of the preclinical Bleomycin...
Behind the Scenes: The Role of R&D in OracleBio
In July 2021, the creation of OracleBio’s dedicated Research & Development group marked an important milestone in our growth strategy. In this article, we go behind the scenes and take a retrospective look at what we have achieved over the past year, and give you...
The integration of Deep Learning methods to improve Nuclei Detection and Segmentation
In this article, we will briefly discuss different methods to detect and segment nuclei and in particular, give examples of how artificial intelligence (AI) Deep Learning (DL) methods are increasingly being applied within our organisation to streamline our image...
Using AI to assess Tertiary Lymphoid Structures in H&E and mIF stained Liver tissue
Following on from our previous article on Tertiary Lymphoid Structures (TLS), in which OracleBio clinical pathologist Gabriele Kohnen discussed the potential role of Tertiary Lymphoid Structures in normal and diseased tissues, this article describes some recent work...
Tertiary Lymphoid Structures and their role within the Immune System
In this article, OracleBio’s Senior Clinical Pathologist, Dr. Gabriele Kohnen, gives her perspective on the proposed role of tertiary lymphoid structures within the immune system and how better understanding their prevalence, cellular content and distribution may...
Where does Cancer come from? – Cancer precursors and their terminology
In this article, OracleBio Senior Clinical Pathologist, Dr. James Going, talks about the importance of understanding where cancer comes from as we seek earlier detection and appropriate treatment.A neoplasm is a population of abnormal cells which persist and...
Using Deep Learning to address Staining Variance across Multiplex IF images
Multiplex IF assays are highly valuable in generating data that enables a deeper understanding of cell phenotypes, their functional status, and spatial relationships within tissues across different diseases or therapeutic interventions. However, the staining of...
Appraise, Action, Adapt & Adopt – Our continuous improvements in GCP
Earlier this year, we announced that OracleBio is now conducting quantitative image analysis on clinical trial samples in accordance with Good Clinical Practices (GCP). Having recognised these standards, it is important to ensure that this high-level quality is...
Still at the Cutting Edge: Microtomy and Digital Pathology
In 2012, my friend and colleague Dr. Gabriele Kohnen salvaged three identical old microtomes from a skip (dumpster for our friends in the US!). After storing them in her garage for a decade, she gave them to me. I guessed they might date from the 1930s, but...
OracleBio’s green journey so far – Our road to sustainability
As a Glasgow-born company, we're immensely proud to see COP26 being hosted in our home city. With the Climate Change Conference in mind, it's a good time for us to reflect on our own actions and how we're helping tackle climate change as a company and as individuals....
Digital Pathology Today Podcast with John Waller
In this podcast, our Chief Operations Officer & founder, John Waller, was invited onto the hugely popular Digital Pathology Today podcast. John and the podcast host, Dr. Joseph Anderson, chat about OracleBio’s humble beginnings and our quantitative digital...