Respiratory Function and Quantitative Measurement of Fibrosis in a Rat Model of Bleomycin-Induced Lung Fibrosis

OracleBio data was presented on a poster at the American Thoracic Society Annual Conference, which took place on the 19th – 24th May 2017. The poster, produced in collaboration with Charles River, is entitled ‘Respiratory Function and Quantitative Measurement of Fibrosis in a Rat Model of Bleomycin-Induced Lung Fibrosis’ and is available to view and download below.

Click here to view our download the posterRespiratory Function and Quantitative Measurement of Fibrosis in a Rat Model of Bleomycin-Induced Lung Fibrosis Poster

The poster shows data from a study which aimed to determine whether impaired lung function in conscious rats could be correlated with the extent of lung fibrosis as assessed by quantitative image analysis. The poster concludes that lung function measurements, and specifically respiratory rate, are significantly correlated with the extent of lung fibrosis as assessed by quantitative morphology on fixed lung sections. These data suggest that in-life respiratory rate measurements may be a useful method to help evaluate efficacy in studies to evaluate new treatments for fibrosis.

To find out more about OracleBio’s digital pathology services to support Respiratory R&D, please contact us. 

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