OracleBio presented a poster at the 2017 Annual Meeting of the American Association for Cancer Research (AACR), on Sunday 2nd April in Washington D.C. The poster, made in collaboration with E-Therapeutics, is entitled ‘Evaluation of ETS2101 in Combination with anti-mCTLA4 Monoclonal Antibody on CD4 and CD8 TILs in a Subcutaneous CT-26 Colorectal Cancer Model’ and is provided in full below.
The poster shows data from a study in which immunohistochemistry (IHC) was used in combination with digital image analysis to quantify CD4+ and CD8+ Tumor Infiltrating Lymphocytes (TILs) in subcutaneous colorectal cancer tumours (CT-26) treated with ETS2101 in combination with an anti-mCTLA4 checkpoint inhibitor. The study demonstrates how IHC combined with image analysis can be utilized to evaluate therapeutic response on TILs within the context of their tumor microenvironment.
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